منابع مشابه
The Prevalence of Drug-Drug Interaction and Inappropriate Drug Prescription Among the Elderly in Kashan
Background: Drug-drug Interaction (DDI) among the elderly is one of the major healthcare challenges worldwide. The present study assessed the rates of DDI and inappropriate drug prescription among the elderly in Kashan City, Iran. Methods: This descriptive-analytical study was designed, conducted, and reported according to the guideline of Strengthening the Reporting of Observational Studies ...
متن کاملDrug treatment of hypertension in the elderly: a meta-analysis.
PURPOSE A meta-analysis of the effect of antihypertensive drug treatment on mortality and morbidity in elderly patients. DATA SOURCES A literature search of published articles from January 1980 to February 1992. STUDY SELECTION Randomized controlled trials of drug treatment of hypertension with end points for elderly patients reported separately. DATA EXTRACTION Mortality or morbidity end...
متن کاملTreatment of Depression in the Elderly: A Systematic Review
Depression is a common symptom and a major public health problem in the elderly. Despite its prevalence and seriousness, depressive disorder in older people remains under-treated. The optimal treatment of depression in later life is crucial, and requires appreciation of several age-related factors such as comorbidity, polypharmacy, altered drug kinetics, variable treatment response and increase...
متن کاملDrug therapy in the elderly.
Drug dosage in the elderly requires an understanding of the age-dependent changes in drug disposition and sensitivity. The most important pharmacokinetic alteration is a decline in renal function, the elderly should therefore be treated as renally insufficient patients. Metabolic clearance is primarily reduced with drugs that display high hepatic extraction, whereas the metabolism of drugs with...
متن کاملDrug therapy in the elderly.
Special considerations must be invoked when prescribing medications for the elderly. Although basic absorption is unchanged, many elderly patients are prone to chronic diarrhea or constipation, either of which may alter intestinal contact time and, thus, absorption. Concurrent use of such drugs as antacids or iron preparations may affect the availability of some compounds for absorption. The pr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMJ
سال: 1977
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.6080.169-a